Nosocomial-acquired sab
Synonym(s)
Hospital-acquired SAB; Nosocomial- acquired SAB; Nosocomial SAH; Nosocomial S.aureus bacteremia
DefinitionThis section has been translated automatically.
Up to 20% of nosocomial bacteremia is caused by S. aureus (Wisplinghoff H et al. 2004). This is caused by the increasing use of intravascular catheters. Patients with hospital-acquired SAB are usually older, often have one or more secondary diseases, an i.v. catheter, respiratory disease, or a surgical wound. Approximately 1/5 of patients develop metastatic complications. Infectious endocarditis (IE) is involved in 6-7% of cases. 20-30% of patients die from their bacteremia. In the U.S., nosocomial S. aureus infections are often MRSA bacteria. This in turn is the cause of more difficult therapy and thus higher treatment costs.
LiteratureThis section has been translated automatically.
- Abramson MA et al (1999) Nosocomial methicillin-resistant and methicillin-susceptible Staphylococcus aureus primary bacteremia: at what costs? Infect Control Hosp Epidemiol 20:408
- Holtfreter S et al (2006) Staphylococcus aureus carriers neutralize superantigens by antibodies specific for their colonizing strain: a potential explanation for their improved prognosis in severe sepsis. J Infect Dis 193: 1275
- Wisplinghoff H et al (2004) Nosocomial bloodstream infections in US hospitals: analysis of 24179 cases from a prospective nationwide surveillance study. Clin Infect Dis 39:309.
- Wyllie DH et al (2006) Mortality after Staphylococcus aureus bacteraemia in two hospitals in Oxfordshire, 1997-2003: cohort study. BMJ 333: 281