Lys-Bradykinin

Last updated on: 21.03.2024

Dieser Artikel auf Deutsch

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

Kallidin, a decapeptide with the sequence H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH, is a bioactive kinin (peptide with an antihypertensive effect) belonging to the plasma kinins. It is formed from the precursor kallidinogen found in blood plasma by the protease kallikrein. It can be converted into bradykinin by the enzyme aminopeptidase.

In addition to its vasodilatory effect, it contracts the smooth muscles of the intestines, uterus and bronchi.

LiteratureThis section has been translated automatically.

  1. Drapeau G et al. (1991) Hypotensive effects of Lys-des-Arg9-bradykinin and metabolically protected agonists of B1 receptors for kinins. J Pharmacol Exp Ther 259: 997-1003.
  2. Drouin JN et al. (1979) Receptors for bradykinin and kallidin. Can J Physiol Pharmacol 57:375-379.

Last updated on: 21.03.2024