Löfgren's syndromeD86.8
Synonym(s)
Acute Boeck's disease; Acute Sarcoidosis; Sarcoidosis acute
HistoryThis section has been translated automatically.
Löfgren, 1946
DefinitionThis section has been translated automatically.
Acute early phase of sarcoidosis which occurs in about 10% of the patients.
Typical triad is:
- Erythema nodosum
- Bilateral swelling of the mediastinal lymph nodes
- (ankle) arthritis
Also: fever, disturbance of the general condition, cough, increase of BSG. Hyp- or anergy in tuberculin test.
ManifestationThis section has been translated automatically.
Preferred among young women.
External therapyThis section has been translated automatically.
According to the erythema nodosum.
Internal therapyThis section has been translated automatically.
The value of systemic glucocorticoids (e.g. Decortin H initial 40-50 mg/day p.o., reduction by clinic for 12 months) is controversial. The long-term prognosis seems to be equally favourable with and without glucocorticoids.
Progression/forecastThis section has been translated automatically.
Favorable, spontaneous remission in over 95% of cases.
LiteratureThis section has been translated automatically.
- Petraityte J et al (2015) Acute form of sarcoidosis: Löfgren's syndrome. Act Dermatol 41: 152-154
- v. Stebut E (2015) Sarcoidosis. dermatologist 66: 549-563