GPR55 gene

Last updated on: 16.05.2021

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DefinitionThis section has been translated automatically.

The GPR55 gene, also known as the G protein-coupled receptor55 gene, is located on chromosome 2q37.1 and encodes a protein belonging to the G protein-coupled receptor superfamily.

General informationThis section has been translated automatically.

The encoded integral membrane protein is probably a cannabinoid receptor . It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. The GPR55 gene may play a role in bone physiology by regulating osteoclast number and function.

Diseases associated with GPR55 include cannabis abuse and lysine-uric protein intolerance. An important paralog of this gene is GPR35.

LiteratureThis section has been translated automatically.

  1. Cho YJ et al (2020) Ginseng Gintonin Contains Ligands for GPR40 and GPR55. Molecules 25:1102
  2. Celorrio M et al (2017) GPR55: A therapeutic target for Parkinson's disease? Neuropharmacology 125:319-332.

Last updated on: 16.05.2021