DNASE1L3 Gene

Last updated on: 08.04.2022

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DefinitionThis section has been translated automatically.

The DNASE1L3 gene (DNASE1L3 stands for "Deoxyribonuclease 1 Like 3") is a protein coding gene located on chromosome 3p14.3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

LiteratureThis section has been translated automatically.

Al-Mayouf SM et al (2011) Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus. Nature Genet 43: 1186-1188.
International Consortium for Systemic Lupus Erythematosus Genetics et al. (2008) Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nature Genet 40: 204-210.
Zervou MI et al. (2020) Association of the DNASE1L3 rs35677470 polymorphism with systemic lupus erythematosus, rheumatoid arthritis and systemic sclerosis: Structural biological insights. Mol Med Rep 22: 4492-4498.

Last updated on: 08.04.2022