DEG

Last updated on: 09.04.2025

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DefinitionThis section has been translated automatically.

In genetics, DEG stands for: Differentially expressed genes. These terms originate from genome research, in particular from transcriptome analysis (e.g. using RNA-Seq). Genes are considered to be differentially expressed if their expression levels (i.e. their ability to translate them into mRNA) differ significantly between two or more conditions. Examples of such conditions are:

diseased vs. healthy
treated vs. untreated
Tissue A vs. tissue B
Cell line 1 vs. cell line 2

Note(s)This section has been translated automatically.

The identification of DEGs helps to understand:

which genes are involved in certain diseases,
how cells react to drugs,
the molecular mechanisms behind physiological differences.

Last updated on: 09.04.2025