Antacids

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Medicinal product for the treatment of complaints due to acidosis of the stomach.

For the most important antacids see Table 1.

IndicationThis section has been translated automatically.

In dermatology, antacids play a role in particular as concomitant medication in systemic therapies with glucocorticoids as well as immunosuppressive or cytostatic therapies.

Limited indicationThis section has been translated automatically.

Intestinal stenosis, hypophosphatemia, gastric outlet stenosis, renal insufficiency, constipation.

Undesirable effectsThis section has been translated automatically.

CNS disorders, anaemia, appetite disorders, constipation, osteomalacia (in dialysis patients), aluminium intoxication in long-term use.

InteractionsThis section has been translated automatically.

s. Table 2.

TablesThis section has been translated automatically.

Overview of the most important antacids and their dosage

Group/Active substance

Dosage

Finished preparation

Aluminium compounds

Aluminium hydroxide

3-4 times/day 2 tbl. p.o. after meals

Tepilta

Magnesium compounds

Magnesium carbonate

If required, chew or suck 1-2 tbl. finely

Palmicol

Aluminium-Magnesium Compounds

Hydrotalcite

1-2 h after the meals 2 tbl. p.o. each

Talcid

Magaldrate

4 times/day after meals 1-2 tbl. or 1 bag p.o.

Riopan

Carbaldrat

1-2 tbl/teel/btl. between meals and before bed

Compensation

Silicates

Aluminium magnesium silicopolyhydrate

Chew 2-3 tbl. intensively several times a day

Ultilac

Aluminium magnesium silicate hydrate

Suck or chew 1-2 tbl. several times a day

Gelusil

Combinations

Aluminium hydroxide-magnesium hydroxide

After the meals 1-2 tbl. or 1-2 bags p.o.

Maaloxan

Magnesium carbonate-calcium carbonate

If required 1-2 tbl., up to 3 times/day p.o.

Rennie

aluminium-magnesium-silicate hydrate + milk powder

Suck or chew 1-2 tbl. several times a day or dissolve and ingest the contents of 1-2 bags in ¼ glass of water

Gelusil-Lac


Significant interactions of antacids

Allopurinol

Allopurinol level ↓, take antacid 3 hours before allopurinol

Atenolol

Atenolol Mirrors ↓

Biphosphonates

Biphosphonate levels ↓

Chenodesoxycholic acid

Chenodesoxycholic acid levels ↓

quinine

quinine levels ↓

Cimetidine

Cimetidine level ↓, take in 2 hours intervals

Ciprofloxacin

Ciprofloxacin levels ↓

Iron

Iron Mirrors ↓

Cardiac glycosides

Glycoside levels ↓

Hydroxychloroquine

Hydroxychloroquine Mirror ↓, to be taken 4 hours apart

Isoniazid

Isoniazid mirror ↓

Itraconazole

Itraconazole level ↓, to be taken 2 hours apart

Ketoconazole

Ketoconazole level ↓, to be taken 2 hours apart

Misoprostol

Misoprostol levels ↓

Food

Fruit juices and wine increase toxicity of Al-containing antacids

Sodium fluoride

Sodium fluoride level ↓, take at intervals of 2 hours

Ofloxacin

Ofloxacin levels ↓

Propanolol

Propanolol levels ↓

Phenytoin

Phenytoin levels ↓

Rifampicin

Rifampicin levels ↓

Tetracyclines

Tetracycline level ↓, to be taken 3 hours apart

Ursodeoxycholic acid

Ursodeoxycholic acid levels ↓

Authors

Last updated on: 29.10.2020