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Targetoid hemosiderotic hemangioma D18.01

Author:Prof. Dr. med. Peter Altmeyer

Co-Autor:Dr. Michael Hambardzumyan

All authors of this article

Last updated on: 06.08.2021

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Synonym(s)

Hobnail hemangioma; Targetoid hemosiderotic hemangioma

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HistoryThis section has been translated automatically.

Santa Cruz and Aronberg, 1988

DefinitionThis section has been translated automatically.

Rare solitary hemangioma occurring at any age with a characteristic clinical aspect similar to a shooting target.

LocalizationThis section has been translated automatically.

Legs, arms, buttocks, hips, chest area. Rarely tongue and gingiva.

Clinical featuresThis section has been translated automatically.

Mostly solitary, 0.2-0.5 cm in Ø, red to brown-red papule/plaque, which in some cases (about 20%) is surrounded by a narrow pale halo and a larger brownish ring (shooting disc aspect). This halo may fade or recede with time. Spontaneous regression of the hemangioma is not uncommon. 'Target-like' hemangioma.

Shallow dark brown variants may lack cocard stratification, causing them to be misrecognized as melanocytic neoplasms.

HistologyThis section has been translated automatically.

Biphasic growth:
  • Superficial dermis: dilated, lacunar, thin-walled vessels lined by prominent "hobnail" endothelia, few intraluminal erythrocytes. Erythrocyte extravasations and hemosiderin deposits are frequently present (see below clinic).
  • Deep dermis: slit-like vascular spaces and haemosiderin deposits located between compressed collagen bundles Smooth muscle actin-positive pericytes are missing (indication of lymphatic differentiation). No mitoses or nuclear atypia.

Differential diagnosisThis section has been translated automatically.

Clinical: Kaposi's sarcoma; Meyerson's nevus; granuloma anulare.

Histological: Angiosarcoma; retiform angioendothelioma; malignant endovascular papillary angioendothelioma; lymphangioma, progressive.

TherapyThis section has been translated automatically.

Excision, no risk of recurrence.

LiteratureThis section has been translated automatically.

  1. Al Dhaybi R et al (2012) Targetoid hemosiderotic hemangiomas (hobnail hemangiomas) are vascular lymphatic malformations: a study of 12 pediatric cases. J Am Acad Dermatol 66:116-120.
  2. Christenson LJ et al. Trauma-induced simulator of targetoid hemosiderotic hemangioma. Am J Dermatopathol 23: 221-223.
  3. Cotell S et al (2003) What is your diagnosis? Targetoid hemosiderotic hemangioma. Cutis 72: 51-52
  4. Guillou L et al (1999) Hobnail hemangioma: A pseudomalignant vascular lesion with a reappraisal of targetoid hemosiderotic hemangioma. Am J Surg Pathol 23: 97-105
  5. Gutte RM et al (2014) Targetoid hemosiderotic hemangioma. Indian Dermatol Online J 5: 559-560.

  6. Kakizaki P et al (2014) Targetoid hemosiderotic hemangioma - Case report. An Bras Dermatol 89:956-959.

  7. Rapini RP, Golitz LE (1990) Targetoid hemosiderotic hemangioma. J Cutan Pathol 17: 233-235.
  8. Santa Cruz DJ, Aronberg J (1988) Targetoid hemosiderotic hemangioma. J Am Acad Dermatol 19: 550-558.
  9. Zaballos P et al (2015) Dermoscopy of Targetoid Hemosiderotic Hemangioma: A Morphological Study of 35 Cases. Dermatology 231:339-344.

Authors

Last updated on: 06.08.2021

Author: Prof. Dr. med. Peter Altmeyer

Co-Autor: Dr. Michael Hambardzumyan