Splendore-hoeppli phenomenon

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

pseudoactinomyotic granulomas; Splendore-Hoeppli Phenomenon

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HistoryThis section has been translated automatically.

Splendore, 1908

DefinitionThis section has been translated automatically.

Histological phenomenon found both in humans (e.g. botryomycosis) and in various animal species in association with organic or inorganic substances. Morphologically, "pseudoactinomycotic" eosinophilic precipitates around organic (e.g. fungal spores) or inorganic foreign materials are found.

Note(s)This section has been translated automatically.

This phenomenon was first described in 1908 by Splendore in sporotrichosis. Later Hoeppli described the phenomenon in schistosomiasis.

LiteratureThis section has been translated automatically.

  1. Choon SE et al (2012) Conidiobolomycosis in a young Malaysian woman showing chronic localized fibrosing leukocytoclastic vasculitis: a case report and meta-analysis focusing on clinicopathologic and therapeutic correlations with outcome. At J Dermatopathol 34: 511-522
  2. Kang JW et al (2010) Intranasal mycetoma-induced splendore-oeppliphenomenon. Otolaryngol Head Neck Surg 142:456-457
  3. Liber AF et al (1973) Splendore-Hoeppli phenomenon about silk sutures in tissue. Arch Pathol 95: 217-220
  4. Völcker HE et al (1985) Eosinophilic, central necrotizing granuloma of the conjunctiva (Splendore-Hoeppli phenomenon). Clinical-histopathological study. Clin Monbl Ophthalmology 186: 254-258

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Last updated on: 29.10.2020