Selective IgA-defciency, mutation in TNFRSF13BD80.2

Last updated on: 12.06.2022

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DefinitionThis section has been translated automatically.

Immunoglobulin A (IgA) deficiency-2 (IGAD2) is caused by a heterozygous, homozygous, or compound heterozygous mutation in the TNFRSF13B gene (604907), which encodes transmembrane activator and CAML interactor (TACI) on chromosome 17p11.2. A mutation in the TNFRSF13B gene can also cause common variable immunodeficiency-2 (CVID2; 240500).

Last updated on: 12.06.2022