Sebaceous gland hyperplasia diffuse presileD23.L
DefinitionThis section has been translated automatically.
ManifestationThis section has been translated automatically.
Occurs in younger to middle age, almost exclusively in men. Also occurring in organ transplant patients under immunosuppression with Ciclosporin A.
LocalizationThis section has been translated automatically.
Face, neck, upper chest.
Clinical featuresThis section has been translated automatically.
Isolated standing or disseminated sowing of densely aggregated, benign, 2-5 mm large, skin-coloured or yellowish-reddish, centrally slightly dented papules. Seborrhoea oleosa.
Differential diagnosisThis section has been translated automatically.
Senile sebaceous gland hyperplasia; functional familial sebaceous gland hyperplasia.
External therapyThis section has been translated automatically.
Long-term therapy with external agents containing tretinoin (e.g. Cordes VAS cream or gel, e.g. Airol solution 0.05%).
Internal therapyThis section has been translated automatically.
In extended cases, isotretinoin (e.g. isotretinoin-ratiopharm; acne normin). Initial sebosuppressive dose of 0.5 mg/kg bw/day, later reduction to 0.3-0.1 mg/kg bw/day. A maintenance dose of 20 mg/day is usually sufficient.
Caution! Anti-conception in women of childbearing age; regular laboratory checks!
Operative therapieThis section has been translated automatically.
Electrocautery with pointed needle, laser therapy(Erbium-YAG laser,CO2 laser) or cryosurgery.
ProphylaxisThis section has been translated automatically.
Consistent light protection with textile as well as chemical/physical light protection agents (e.g. Anthelios).
LiteratureThis section has been translated automatically.
- Kaufmann R (1987) Diffuse (presenile) sebaceous gland hyperplasia, a new entity? dermatologist 38: 31-35
- Zouboulis C et al (2003) Ciclosporin A - induced sebaceous glands hyperplasia. Br J Dermatol 149: 198-200