Rimexolone
DefinitionThis section has been translated automatically.
Glucocorticoid. Non-halogenated synthetic prednisolone derivative.
IndicationThis section has been translated automatically.
- Arthritis/Arthrosis: In the case of inflammation in one or a few joints after unsuccessful general treatment, in chronic polyarthritis (rheumatoid arthritis) and in inflammatory activated arthrosis.
- Eyes: Non-infectious inflammatory diseases of the anterior uvea, the palpebral and bulbar conjunctiva, the cornea and the anterior segment of the eye as well as inflammatory conditions after eye surgery.
Pregnancy/nursing periodThis section has been translated automatically.
Contraindicated in the 1st trimester, should not be used during lactation (insufficient data available).
Dosage and method of useThis section has been translated automatically.
- Arthrosis/arthritis: 10-40 mg of rimexolone (0.25 to 1.0 ml of rimexel as suspension) intra-articular. The dosage depends on the size of the joint to be treated and the severity of the symptoms; as a rule, 40 mg of Rimexolon are required for large joints (knee, hip), 20 mg for medium-sized joints (elbow, shoulder) and 10 mg for small joints (finger joints, metacarpal finger joints) (single dose = daily dose).
- Eye: Postoperative inflammation: First 24 hours after surgery and in the following 2 weeks, 4 times/day, 1 trp. should be applied into the conjunctival sac. Steroid-sensitive inflammation: 4 times/day or more often 1 trp. into the conjunctival sac. The duration of use should not exceed 4 weeks. Uveitis: During the first week, 1 trp. should be applied to the conjunctival sac once an hour during the day, every 2 hours during the second week and 4 times/day during the third week. During the first 4 days of week 4, drop 1 drop twice a day and during the last 3 days 1 drop a day in the affected eye.
Standard concentrationThis section has been translated automatically.
1% (10 mg/ml) in eye drops.
Undesirable effectsThis section has been translated automatically.
Blurred vision, secretion formation, sensations, eye pain and foreign body sensation, hyperemia, ocular pruritus, stickiness, increased fibrin formation, dry eye, conjunctival oedema, corneal discoloration, keratitis, increased tear secretion, light sensitivity, corneal ulcer, etc.
ContraindicationThis section has been translated automatically.
Cave! No i.v. application!, joint infections, severe general infections, bacteremia, joint instability, bleeding tendency, periarticular calcification, serious contraindications for systemic glucocorticoid therapy, avascular bone necrosis, Charcot joint (Charcot arthropathy).
PreparationsThis section has been translated automatically.
Rimexel, Vexol