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Reflected light microscopy, radial streaming

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Digitiform offshoots; peripheral stripes; radial extensions

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DefinitionThis section has been translated automatically.

Reflected light microscopic phenomenon of stripe-shaped extensions in the periphery of a pigmented skin lesion.

General informationThis section has been translated automatically.

Reflected light microscopy: Radially arranged, finger-shaped, brown-black melanin pigment stripes pointing into the periphery taper at the ends, in contrast to the bulbously widening pseudopodia. At their longitudinal edges the stripes are sometimes finely serrated.

OccurrenceThis section has been translated automatically.

Within the group of pigment cell tumors, the characteristic of "radial streaming" has a specificity of more than 90% for malignant melanomas (sensitivity about 15%). Spindle cell nevi ( Naevus Spitz) and pigmented basal cell carcinomas may show this phenomenon, rarely junctional nevi and highly pigmented Verrucae seborrhoicae.

HistologyThis section has been translated automatically.

Radial-striar confluent junctional melanocyte nests with massive transepidermal stripe-like pigment discharge.

LiteratureThis section has been translated automatically.

  1. Bahmer FA, Fritsch P et al (1990) Diagnostic criteria in reflected light microscopy. Dermatologist 41: 513-514
  2. Bauer J et al (2001) Dermatoscopy turns histopathologist's attention to the suspicious area in melanocytic lesions. Arch Dermatol 137: 1338-1340
  3. Haas N, Ernst TM, Stüttgen G (1984) Macro photography in transmitted light. A contribution to the horizontal structural analysis of pigmented skin tumors. Z Hautkr 59: 985-989
  4. Kenet RO, Kang S, Kenet BJ, Fitzpatrick TB, Sober AJ, Barnhill RL (1993) Clinical diagnosis of pigmented lesions using digital epiluminescence microscopy. Arch Dermatol 129: 157-174
  5. Nilles M, Boedecker RH, Schill WB (1994) Surface microscopy of naevi and melanomas - clues to melanoma. Br J Dermatol 130: 349-355
  6. Robinson JK et al (2004) Digital epiluminescence microscopy monitoring of high-risk patients. Arch Dermatol 140: 49-56

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer