Reflected light microscopy, angiectatic basic pattern

Reflected light microscopy: As a typical indication of the presence of a pigment cell tumor, there are usually discrete brownish cloudy areas or weakly pronounced background pigmentation. Already in in-situ melanomas, the vascular architecture of a neovascularisation triggered by neoplastic-inflammatory processes may mask other melanoma-typical incident light criteria. Widened capillaries with pronounced caliber fluctuations, aneurysmatic sacculations and microscopic hemorrhages are characteristic. Polymorphic vessel figures phenotypically resemble Greek lower case letters (minuscule pattern). Especially initial cutaneous or epidermotropic melanoma metastases often have angiectatic basic architectures.