Prepuberal hypertrichosisL68.-

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

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Synonym(s)

Constitutional generalized hypertrichosis; Prepuberal hypertrichia; Prepubertal hypertrichosis

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DefinitionThis section has been translated automatically.

Generalized, for the respective body part untypically strong hair, in diffuse androgen-independent. Hair-biologically, a transition from vellus hair to terminal hair takes place.

Occurrence/EpidemiologyThis section has been translated automatically.

There are no exact data on the incidence of prepubertal hypertrichosis; probably not rare; familial occurrence possible.

EtiopathogenesisThis section has been translated automatically.

One study showed a slight increase in peripheral 5alpha-reductase activity in patients with a normal androgen profile (Gryngarten M et al. 2000)

Clinical featuresThis section has been translated automatically.

Conspicuously thick and dark hair in the area of forehead, eyebrows, back, shoulders and upper extremities, deep hairline at the temples, intercapular hair vertebrae and strong hair on the elbows.

DiagnosisThis section has been translated automatically.

Clinical picture with the typical androgen-independent distribution pattern of terminal hair.

TherapyThis section has been translated automatically.

Symptomatic, shaving, depilation, wax removal, laser depilation. Remark: During mechanical depilation, e.g. wax removal, there is a risk of transformation of vellus hairs into terminal hairs.

Progression/forecastThis section has been translated automatically.

Hpertrichosis persists throughout life. An increase in hypertrichosis is to be expected especially in men with dark skin type.

LiteratureThis section has been translated automatically.

  1. Barth JH et al (1988) Prepubertal hypertrichosis: normal or abnormal? Arch Dis Child 63:666-668.
  2. Gryngarten M et al (2000) Clinical assessment and serum hormonal profile in prepubertal hypertrichosis. Horm Res 54:20-25.
  3. Hernandez MI et al (2014) Hormonal profile and androgen receptor study in prepubertal girls with hypertrichosis. Int J Pediatr Endocrinol 6:doi:10.1186/1687-9856-2014-6
  4. Trüeb RM et al (1994) Prepubertal hypertrichosis. Switzerland Med Wschr. 124: 595-560

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer