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Povidone-iodine
Synonym(s)
Polyvidonum-Iodine; Polyvinylpyrrolidone-iodine; Polyvinylpyrrolidonum-iodine; Povidone-iodine; PVP Iodine; PVP-iodine (INCI)
DefinitionThis section has been translated automatically.
Disinfectant. Consists of polyvinylpyrrolidone of different chain length and contains iodine in a complex bond. Its disinfecting effect is ultimately based on the action of free iodine.
The substance is soluble in water and ethanol, but not in acetone and ether.
IndicationThis section has been translated automatically.
Superficial skin and mucous membrane infections, burns.
Limited indicationThis section has been translated automatically.
Pregnancy, infants < 6 months, thyroid diseases.
Dosage and method of useThis section has been translated automatically.
- Solution/Cream/Ointment/Gel: Apply once/day to the affected areas.
- For infections in the vaginal area: 1 vaginal suppository of 200 mg or an applicator filling (5 g) of the 10% gel should be inserted deep into the vagina.
Standard concentrationThis section has been translated automatically.
- 1% solution for flushing body cavities.
- 7.5% solution for mouth rinsing.
- 3,25-10% solution/cream/ointment/gel.
Undesirable effectsThis section has been translated automatically.
Allergic reactions ( contact allergy). Povidone-iodine is a common contact allergen in the IVDK collective. The substance has a high irritant potential (Ammann PM et al. 2018).
Pain when applied to the wounds, metabolic acidosis, electrolyte disorders, hyperthyroidism, thyrotoxicosis (in case of latent thyroid dysfunction), renal insufficiency, delayed wound healing.
Anaphylactic reactions have also been described to the carrier substance (see below polyvinylpyrrolidone).
InteractionsThis section has been translated automatically.
Topical IFN (denaturation of IFN), highly local toxic reactions and burns caused by mercury compounds.
ContraindicationThis section has been translated automatically.
Lactation, iodine allergy, dermatitis herpetiformis, radioiodine therapy, acne vulgaris.
Recipe(s)This section has been translated automatically.
PreparationsThis section has been translated automatically.
Betaisodona, Traumasept
LiteratureThis section has been translated automatically.
- Ammann PM et al (2018) Disinfectants. Allergo J 27:16-18