Term for an extensive thickening and hardening of the skin as a result of interstitial connective tissue hypertrophy or cellular infiltration, e.g. in mycosis fungoides.
Occurs in the following underlying diseases, among others:
- Induration in systemic scleroderma
- Cutis verticis gyrata
- Pachydermoperiostosis, primary
- Pachydermoperiostosis, symptomatic
- Lichen myxoedematosus.
Secondary in chronic edema, elephantiasis.