OnychomatrixomaD21.1/21.2
Synonym(s)
HistoryThis section has been translated automatically.
Baran and Kint, 1992
DefinitionThis section has been translated automatically.
Rare, benign (the dignity of the tumor is not conclusively clarified), only very slowly growing, fibroepithelial tumor of the nail matrix which leads to a painless, longitudinal proliferation, distension and yellow-brown discoloration and finally to a complete destruction of the nail matrix. Small splinter hemorrhages are often present in the proximal part of the nail.
ManifestationThis section has been translated automatically.
Affected are 30-50 year olds.
Clinical featuresThis section has been translated automatically.
Clinically, there is a painless, elongated-streaked discoloration and distension with thickening of the nail plate, the surface of which initially remains intact. On frontal view of the nail edge, a yellowish crumbly cystic-wabby (DD: onychomycosis) enforcement of the nail matrix becomes visible. This corresponds to the tumor.
HistologyThis section has been translated automatically.
Broad-based fibroepithelial growth that adapts to the nail contour. The polymorphic tumor stroma shows Cd34 positivity, further positivity for S100, actin and desmin. Furthermore described are myxoid stroma formations.
Differential diagnosisThis section has been translated automatically.
Subungual verrucous carcinoma; dorsal cyst; digital fibrokeratome.
TherapyThis section has been translated automatically.
Excision in a healthy person; the tumour tends to recur, so that careful attention must be paid to a careful excision in a healthy person.
LiteratureThis section has been translated automatically.
- Baran R, Kint A (1992) Onychomatrixoma. Filamentous tufted tumour in the matrix of a funnel-shaped nail: a new entity (report of three cases) Br J Dermatol 126:510-515
- Fernandez-Flores' A et al (2014) Pleomorphic onychomatricoma. J CutanPathol 41:555-560
- Oztürk Durmaz E et al.(2013) Onychomatricomamasquerading as candidal onychomycosis and paronychia. Acta Dermatovenerol Croat 21:198-201
- Stewart CL et al(2015) Myxoid Onychomatricoma: An Unusual Variantof a Rare Nail Unit Tumor. At J Dermatopathol PubMed PMID: 25830718.
- Tavares GT et al (2015) Onychomatricoma: a tumorunknown to dermatologists. On Bras Dermatol 90: 265-267
- Wang L et al (2014) Nail bed onychomatricoma. J Cutan catholic 41:783-786