Melanocyte-stimulating hormone

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

Dieser Artikel auf Deutsch

Synonym(s)

Melanotropins; MSH

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

A group of peptide hormones formed in the hypothalamus and intermediate pituitary lobes which activate the same group of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). They are processed from the protein proopiomelanocortin (POMC). MSH regulate melanin synthesis in melanocytes, melanocyte expansion and pigment dispersion. They also limit fever reactions and are involved in the regulation of hunger and sexual functions.

ClassificationThis section has been translated automatically.

The group of melanotropins (MSH) form:
  • alpha-MSH
  • beta-MSH
  • gamma-MSH.
The group of melanocortins includes:
  • ACTH.

Note(s)This section has been translated automatically.

A synthetic MSH analogue, Bremelanotide, was in clinical development because of its aphrodisiac effect (erectile dysfunction). Another MSH analogue, Melanotan for skin tanning is currently still in clinical development but is illegally marketed as a tanning agent in various countries.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer