Melan-a

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

MART1

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DefinitionThis section has been translated automatically.

Melan-A (MART1) serves as an important immunohistological marker for melanocytes and melanocytic tumors. The available antibody is more sensitive than HMB45
and the detection of Melan-A is positive in epidermal and dermal melanocytes, in steroid producing cells (adrenal gland) and in cutaneous clear cell sarcoma.

LiteratureThis section has been translated automatically.

  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer Publishing House Berlin-Heidelberg p. 30.
  2. Takamura S et al. (2015) Case of clear cell sarcoma in the left buttock in which serum neuron-specific enolase was a useful marker for monitoring disease progression. J Dermatol 42:621-624.
  3. Tazzari M et al (2015) Melan-A/MART-1 immunity in a EWS-ATF1 translocated clear cell sarcoma patient treated with sunitinib: a case report. BMC Cancer 15:58.

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Last updated on: 29.10.2020