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Kaposi's sarcoma epidemicC46.-
Synonym(s)
DefinitionThis section has been translated automatically.
Rare multifocal angioproliferative neoplasia occurring primarily in the skin and secondarily also in other organs. Kaposi's sarcoma occurs spontaneously or as part of an HIV infection (infectious angiogenesis).
Occurrence/EpidemiologyThis section has been translated automatically.
Incidence of HIV-associated, epidemic Kaposi sarcoma: in 5-7% of HIV-infected persons. In earlier times of epidemic Kaposi's sarcoma that could not be treated adequately, the incidence was > 25% of HIV-infected persons.
EtiopathogenesisThis section has been translated automatically.
LocalizationThis section has been translated automatically.
Predilection sites are the face (tip of the nose), trunk, genitals, oral mucosa.
Clinical featuresThis section has been translated automatically.
Initially brown-red to violet spots, from which plaque-like and nodular tumours develop. Tendency to confluence and formation of new foci in the marginal area. Tendency to ulceration (especially mucous membrane lesions). In case of trunk infestation mostly exanthematic spread of the skin lesions with characteristic arrangement along the skin cleft lines. Disturbed lymph drainage leads to elephantiasis-like oedemas. Infestation of lymph nodes, more rarely of the gastrointestinal tract, liver, lungs or heart is possible.