Inosine
Synonym(s)
Dimepranol; Dimepranol acetamidobenzoate
DefinitionThis section has been translated automatically.
Synthetic derivative of purine with immunomodulatory and virustatic properties. Intermediate product of purine metabolism (purine nucleoside). Effectiveness is controversial.
IndicationThis section has been translated automatically.
For immune stimulation in viral diseases, especially subacute sclerosing panencephalitis, herpes simplex, zoster, measles, cytomegaly and Epstein-Barr virus infection.
Pregnancy/nursing periodThis section has been translated automatically.
Strict indication position! There is no sufficient experience with pregnant women or mothers in the lactation period.
Dosage and method of useThis section has been translated automatically.
- Herpes simplex infections: adults 6-8 tbl/day depending on the severity of the disease (one tbl every 2-3 hours), children 1/2-6 tbl spread over several doses throughout the day (50-100 mg active substance/kg bw/day).
- Viral infections in immunocompromised patients: adults: 50 mg divided into 3-5 doses, children 100 mg active substance mixture/kg bw/day divided into 2-4 doses.
Undesirable effectsThis section has been translated automatically.
ContraindicationThis section has been translated automatically.
Purine metabolism disorders (gout, hyperuricemia), renal insufficiency, urinary and kidney stone disorders, tendency to extrasystoles, cerebral seizure disorders, gastric disorders, autoimmune disorders and celiac disease.
PreparationsThis section has been translated automatically.
Isoprinosines