Inclusion body conjunctivitisA74.0
Synonym(s)
neonatal inclusion blenorrhea; Paratrachoma; Swimming conjunctivitis; Trachoma inclusion conjunctivitis
DefinitionThis section has been translated automatically.
Acute purulent conjunctivitis caused by Chlamydia trachomatis.
EtiopathogenesisThis section has been translated automatically.
Infection due to bathing in insufficiently renewed waters. Inclusion blenorrhoea of newborns mostly infection during passage through the birth canal in case of chlamydial infection of the mother.
Clinical featuresThis section has been translated automatically.
Incubation period 8-14 days. Acute conjunctivitis with redness, swelling and aqueous-mucosal conjunctival secretion as well as grayish red, sagocorn-shaped follicles or papillary growths. Possible involvement of the preauricular lymph nodes or the nasopharyngeal cavity.
HistologyThis section has been translated automatically.
Inclusion corpuscles in the epithelium of the transitional folds and conjunctiva (smear) = Prowazek-Halberstädter corpuscles.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
- Adults: In case of swimming pool conjunctivitis, no swimming in public waters! External and internal antibiotic therapy see table 1.
- Newborn babies: Instead of the Crédéan prophylaxis with silver nitrate solution against the transmission of gonococci via the birth canal, 1% erythromycin (e.g. Ecolicin eye drops or eye ointment) are used prophylactically in many places today to help combat chlamydia, which is more frequently transmitted to babies at birth. It should be remembered that (re-)infection can occur via the nasopharynx in the newborn despite prophylaxis.
- Pregnant women: If a pregnant woman is known to have a genital infection, treatment with erythromycin is indicated to avoid complications, e.g. premature birth. Medication see table 1. course can last for months.
Progression/forecastThis section has been translated automatically.
Months of progression, healing without scarring. Favorable for newborns.
TablesThis section has been translated automatically.
Therapy for inclusion body disease
|
antibiotic |
Example preparation |
Dosage |
Duration |
|
adult conjunctivitis |
easy |
Erythromycin |
Ecolicin |
1 trp. or 5 mm ointment strand every 1-2 hours |
until healing |
heavy |
Doxycycline |
Doxycycline Hayman |
2 times/day 100 mg p.o. |
10-14 days |
|
stubborn |
Sulfonamides or chloramphenicol |
Posifenicol C 1% Eye ointment |
5 mm ointment strand every 1-2 hours |
7-14 days |
|
Conjunctivitis and pneumonia in the newborn |
Prophylaxis |
Erythromycin |
Ecolicin Trp. |
1-2 Trp. |
once |
Therapy |
Erythromycin |
Ecolicin Trp. |
1-2 trp. every 2-3 hours |
every 14 days |
|
Monomycin baby juice |
50 mg/kg bw/day |
||||
Genital infection in pregnant women |
|
Erythromycin |
Erythrocin Filmbl. |
4 times/day 500 mg p.o. |
7-10 days |
LiteratureThis section has been translated automatically.
- Bersudsky V et al (1999) Diagnosis of chlamydial infection by direct enzyme-linked immunoassay and polymerase chain reaction in patients with acute follicular conjunctivitis. Graefes Arch Clin Exp Ophthalmol 237: 617-620
- Gscheit F (1986) Genital Chlamydia infections. dermatologist 37: 312-319
- Katusic D et al (2003) Azithromycin vs doxycycline in the treatment of inclusion conjunctivitis. Am J Ophthalmol 135: 447-451
- Lietman T, Fry A (2001) Can we eliminate trachoma? Br J Ophthalmol 85: 385-387
- West S (2000) The red eye. N Engl J Med 343: 1577