Images (2)
Incident light microscopy, blue-in-pink zone
Synonym(s)
blue-in-pink area; blue-red area
DefinitionThis section has been translated automatically.
Oval or polygonal areas of about 0.2-0.4 mm in size, rarely more than 1.0 mm in size, with bluish streaky pigment densifications projected into the incident light plane against a pink background.
General informationThis section has been translated automatically.
Incident light microscopy: In the centre or border of the lesion there are usually circumscribed oval or polygonal areas with bluish stripes or agglomerates (melanophagus accumulations) against a pink background (neovascularization). In some cases the lateral edges of the stripes show small serrations. Bluish pigment densities are loosely aggregated like dots.
OccurrenceThis section has been translated automatically.
Within the group of pigment cell tumors, malignant melanomas have a specificity of over 80% (sensitivity 36%) for the blue-in-pink zone phenomenon under the reflected light microscope. More rarely, such changes are found in dysplastic nevi, combined nevi, recurrent nevi, pointed nevi or basal cell carcinomas.
HistologyThis section has been translated automatically.
Melanophages and/or infiltrating tumor cell strands are located within capillary vascularized, neovascularized fibrosis zones. The reteleistes are completely destroyed in this region.
LiteratureThis section has been translated automatically.
- Schulz H (1994) Malignant melanomas in reflected light microscopy. dermatologist 45: 15-19
- Proud W, Braun-Falco O, Bilek P, Landthaler M, Burgdorf WHC, Cognetta AB (2002) Color atlas of dermatoscopy. Blackwell, Berlin Vienna