Immunotherapy, specific, oral, tablet therapy
Synonym(s)
Grazax
DefinitionThis section has been translated automatically.
Allergen preparation for sublingual immunotherapy for grass pollen allergy.
IndicationThis section has been translated automatically.
For the treatment of grass pollen-induced pollinosis or rhinoconjunctivitis allergica in adults when SCIT is not an option.
Limited indicationThis section has been translated automatically.
- Fish Allergy
- Tooth extractions or other operations in the oral cavity within the last 7 days before the start of treatment.
Pregnancy/nursing periodThis section has been translated automatically.
Treatment not recommended during pregnancy, currently no reliable data available for use during lactation.
Dosage and method of useThis section has been translated automatically.
1 x/day 1 tbl. p.o.; therapy start 4 months before the start of the grass pollen season. Therapy is then continued during the grass pollen season.
Undesirable effectsThis section has been translated automatically.
- Side effects are usually temporary and occur as oral allergy syndrome restricted to the oral cavity. The risk of systemic or serious side effects is less than with SCIT.
- According to manufacturer's information/study results:
- Particularly common: facial itching, neck irritation, sneezing, itching and swelling of the neck.
- Common: conjunctivitis, rhinitis, angioedema, clinical symptoms of tonsillitis, pulmonary symptoms, dyspnea, gastrointestinal symptoms. Coughing, disturbance of general well-being (fatigue).
- Occasionally: urticaria, pain and inflammation of the mouth, blisters on the lips.
ContraindicationThis section has been translated automatically.
- Hypersensitivity to components of the tablet.
- Diseases of the immune system.
- Severe bronchial asthma.
- Malignant diseases.
- Inflammations in the oral cavity.
PreparationsThis section has been translated automatically.
Grazax (ALK-Scherax)
Note(s)This section has been translated automatically.
Grazax contains allergens from grass pollen of timothy grass (Phleum pratense).
LiteratureThis section has been translated automatically.
- Dahl R et al (2006) Efficacy and safety of sublingual immunotherapy with grass allergen tablets for seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol 118: 434-440