Immunoglobulins, specific
Synonym(s)
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Overview of the most important specific immunoglobulins
Immunoglobulin |
Indication |
Dosage |
Finished preparation |
hepatitis B |
Hepatitis B prophylaxis in case of increased risk of infection (dialysis, needlestick injuries) |
Simultaneous prophylaxis (simultaneously with the 1st dose of HBV vaccine): 0.06 ml/kg bw i.m. For newborns: total dose of 1 ml i.m. |
Hepatitis B immunoglobulin Behring |
In case of exposure/suspicion (no simultaneous prophylaxis with HBV vaccine): at least 0.06 ml/kg bw i.m., repeat with same dose after 4 weeks. | |||
In case of massive exposure (e.g. after transfusion of HBV-infected blood or blood components): at least 0.12 ml/kg bw i.m. | |||
Continuous prophylaxis 0.06 ml/kg bw at intervals of 3 months | |||
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CMV |
Prophylaxis of CMV infections after transplantation or in HIV patients with < 50 CD4 cells/μl |
50-100 IU/kg bw i.v. every 14 days, according to clinical course |
Cytotect |
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VZV |
Prophylaxis of varicella in immunocompromised patients, |
1 ml/kg bw i.v. within 3 days after exposure |
e.g. Varitect |
Herpes zoster in immunocompromised patients |
2 ml/kg bw i.v. |
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