Hydroxyphenoxy-propionic acid

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

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Synonym(s)

hydroxyphenoxy propionic acid; Hydroxyphenoxypropionic acid

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DefinitionThis section has been translated automatically.

Phenolic carboxylic acid which, when applied topically, is intended to lighten the skin. In a small clinical study (n=82) a hydroxyphenoxy-propionic acid formulation was
comparedwith
a 4% hydroquinone cream. The clinical effect was comparable in this study. In melanoma cell cultures hydroxyphenoxy propionic acid inhibits melanone production by inhibiting the melanosome transfer to the keratinocytes.

Note(s)This section has been translated automatically.

In the trade, hydroxyphenoxy-propionic acid formulations are advertised luridly against "age spots". Due to their chemical composition they should only be used after consultation with a dermatologist.

LiteratureThis section has been translated automatically.

  1. Draelos ZD et al (2013) Dyspigmentation, skin physiology, and a novel approach to skin lightening.J Cosmet Dermatol 12:247-253.
  2. Draelos ZD et al (2015) A method for maintaining the clinical results of 4% hydroquinone and 0.025%tretinoin
    with a cosmeceutical formulation.J Drugs Dermatol 14:386-390.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer