HerpanginaB08.5

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 09.05.2023

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Synonym(s)

herpetic pharyngitis; Pharyngitis ulcerative; ulcerative pharyngitis; vesicular pharyngitis

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HistoryThis section has been translated automatically.

Zahorsky, 1920; Cole, 1951

DefinitionThis section has been translated automatically.

Infection of the pharynx by human enterovirus A (coxsackie virus-A) by droplet infection from person to person.

PathogenThis section has been translated automatically.

Coxsackie viruses of groups A2, A4, A5, A6, A8, A10, B4.

Occurrence/EpidemiologyThis section has been translated automatically.

Worldwide occurrence, mainly in summer, leaves permanent immunity

EtiopathogenesisThis section has been translated automatically.

Coxsackie virus infection.

Clinical featuresThis section has been translated automatically.

Incubation period: 2-5 days. Acute fever increase with biphasic fever course. Influenza-catarrhal phenomena. Occurrence of glass pinhead-sized, chain-like arranged, yellowish-pink, frogspawn-like vesicles on the soft palate and the palatal arches. Transformation into smeary-coated erosions with hyperemic surroundings.

Differential diagnosisThis section has been translated automatically.

Gingivostomatitis herpetica: acute course, affects young children (up to 5 years).

Angina plaut-Vincenti: Acute ulcerative tonsillitis due to mixed infection with Treponema vincenti (see spirochetes below), Fusobacterium plauti and other spirochetes, Bacteroides species.

Diphtheria: Whitish, fibrinous, pseudomembranous, firmly adherent, sweet foul smelling coatings on the tonsils, palatal arches and uvula in diphtheria.

Candidiasis: more subacute to chronic course. Two-dimensional whitish coatings.

TherapyThis section has been translated automatically.

Symptomatic. Rinse with wound-healing or astringent pharyngeal therapeutics such as dexpanthenol solution(e.g., Bepanthen®, Dexpanthenol Solution 5% (NRF 7.3.) or chlorhexidine solution (e.g., Chlorhexidine Gluconate Lsg., Rp: Chlorhexidine Mouthwash Solution 0.1 or 0.2% (NRF 7.2.).

Progression/forecastThis section has been translated automatically.

Favorable, healing in 10-14 days.

LiteratureThis section has been translated automatically.

  1. Chawareewong S et al (1978) Neonatal herpangina caused by Coxsackie A-5 virus. J Pediatr 93:492-494.
  2. Cole RM (1951) Studies of Coxsackie viruses: observations on epidemiological aspects of group A viruses. Am J Pub Health 41: 1342

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Last updated on: 09.05.2023