Fibroblast growth factor 23

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

FGF23

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DefinitionThis section has been translated automatically.

The "fibroblast growth factor 23" (FGF23) is a protein of the FGF family, which is responsible for the phosphate metabolism. Its synthesis takes place in bone tissue.

General informationThis section has been translated automatically.

FGF23 has an inhibitory effect on calcitriol synthesis and renal phosphate absorption. This is achieved by inhibition of 1-alpha-hydroxylase and stimulation of 24-hydroxylase. The rareFGF23-producing tumors(phosphaturic mesenchymal tumor) are associated with tumor-associated phosphaturia and consecutive osteomalacia.

LiteratureThis section has been translated automatically.

  1. Qari H (2016) Phosphaturic Mesenchymal Tumor: 2 New Oral Cases and Review of 53 Cases in the Head and Neck. Head and Neck Pathogen 10:192-200.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer