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Dexamethasone
Synonym(s)
9-Fluor-11β,17,21-trihydroxy-16α-methyl-pregna-1,4-dien-3,20-dion; Dexamethasone; Oradexone
DefinitionThis section has been translated automatically.
Medium strength halogenated glucocorticoid.
Half-lifeThis section has been translated automatically.
3–5 h
IndicationThis section has been translated automatically.
Allergic diseases, topical for allergic skin reactions and eczema, emergencies such as anaphylactic shock, status asthmaticus, brain edema.
Dosage and method of useThis section has been translated automatically.
- Eye drops: Apply 2 times/day in the conjunctival sac.
- Creams / Ointments: Apply thinly 1-3 times/day to the affected skin areas.
- Solutions/Crinals: Apply a thin layer 1-3 times/day to the affected areas of skin.
- Systemic: Initially 0.75-16 mg in the morning, then reduction to 1-1.5 mg/day p.o., i.v. or i.m. In emergencies (cerebral edema, anaphylactic shock): Initially 40-100 mg i.v., then 4-8 mg i.v. or i.m. in 2-4 hours intervals over about 8 days. Status asthmaticus: 4-20 mg initial i.v., if necessary another 8-10 mg i.v.
Standard concentrationThis section has been translated automatically.
0.1% eye drops, 0.3-1% in creams and ointments, 0.25-0.3% in solutions
ContraindicationThis section has been translated automatically.
I.m. injection for idiopathic thrombocytopenic purpura, i.v. injection of crystal suspension.
Recipe(s)This section has been translated automatically.
PreparationsThis section has been translated automatically.
Fortecortin, dexamethasone Jenapharm, cortidexasone, Dexa Hexal