Cd68

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Macrosialine

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DefinitionThis section has been translated automatically.

Acronym for"Cluster of differentiation 68".

Note: CD68 labels monocytes, macrophages, mast cells, "plasmacytoid T cells", myeloid progenitor cells. The antibody is useful in the diagnosis of acute and chronic myeloid leukemia (AML and CML).

Structure: 110 kDA

Note: CD68 is a lysosomal antigen: all lysosome-rich cells (granular cells) are CD68+: for example cells of granular cell tumour. Myxofibrosarcoma also shows a high expression of CD68.

LiteratureThis section has been translated automatically.

  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer Publishing House Berlin-Heidelberg p. 28.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer