Cd103

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 15.01.2022

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Synonym(s)

HUMINAE; integrin subunit alpha E; ITGAE

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HistoryThis section has been translated automatically.

CD103 also known as integrin, alpha E or ITGAE is an integrin protein that in humans is encoded by the ITGAE gene located on chromosome 17: 3.71 - 3.8.

Integrins form a family of adhesion molecules expressed on the cell surface of various cells. CD103 is produced by intraepithelial T lymphocytes and by regulatory T cells (Tregs).

Clinically-diagnostically, it serves, among other things, as a marker for tumor cells of hairy cell leukemia.

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Last updated on: 15.01.2022