Cadm antibodies

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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General informationThis section has been translated automatically.

CDAM antibodies - (also MDA5 antibodies) are antibodies against a cytoplasmic 40 kDa protein. CDAM antibodies are found in 50% of cases of "amyopathic dermatomyositis". Patients with this antibody constellation are said to develop, in addition to cutaneous changes, a rapidly progressive lung involvement (mainly described in Asians) and have a poor prognosis.

LiteratureThis section has been translated automatically.

  1. Volc-Place B (2015) Dermatomyositis update. Dermatologist 66:604-610

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer