C-erb-2 oncoprotein

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

HER-2/new

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DefinitionThis section has been translated automatically.

The c-erb-2 oncoprotein is a cytoplasmic epitope that is mainly expressed in breast carcinomas and their metastases. A c-erB-2 overexpression is associated with a poor prognosis. Overexpression of the c-erB-2 oncoprotein is therapeutically relevant in breast cancer. C-erB-2 is an important marker of intaepidermal mammary Paget cells.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer