Images (1)

Angiofibroma cell-richD23.0

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

Dieser Artikel auf Deutsch

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

Benign fibroblastic soft tissue tumor, rarely recurring postoperatively, which occurs preferably in the genital area.

ManifestationThis section has been translated automatically.

Women are more frequently affected than men.

LocalizationThis section has been translated automatically.

Genital area, also extremities.

Clinical featuresThis section has been translated automatically.

Symptomless, firm, reddish or slightly bluish shimmering lumps. The tumours do not grow larger than 3.0 cm in women, but up to 25 cm in men.

HistologyThis section has been translated automatically.

Sharply defined tumour with numerous thick-walled hyalinised vessels, abundant spindle cells and interspersed adipocytes. Mitoses can be numerous. Lipogenic differentiation is not uncommon. The tumor parenchyma often expresses CD34, alpha-smooth muscle actin and desmin, but not S-100 protein and pancytokeratin.

LiteratureThis section has been translated automatically.

  1. Ahmadnia HJ et al (2014) Angiofibroma of the vulva. Cutan Med Surg 18:203-205
  2. Mentzel T (2016) Mesenchymal tumors of the skin. In: Cerroni L et al. histopathology of the skin. Springer-Verlag Berlin Heidelberg New-York S 751-753

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer