Amantadine
DefinitionThis section has been translated automatically.
Dopamine agonist.
IndicationThis section has been translated automatically.
Usually M. Parkinson's, extrapyramidal disorders. In dermatology especially for post-zoster neuralgia.
Limited indicationThis section has been translated automatically.
Lactation period, children < 12 months, age > 65 years, heart failure, hypotension, myasthenia gravis, peripheral edema, tachycardia, narrow-angle glaucoma.
Dosage and method of useThis section has been translated automatically.
Initially 100-200 mg/day p.o., after 1 week 2-3 times/day 100-150 mg.
Undesirable effectsThis section has been translated automatically.
Allergic skin reactions, livedo reticularis, cutis marmorata, CNS disorders, dizziness, visual disorders, photophobia, drop in blood pressure, cardiac arrhythmia, dyspnoea, leukopenia, loss of appetite, dry mouth, nausea.
Notice! Cross-allergy to Tromantadin!
InteractionsThis section has been translated automatically.
s. Table 1.
ContraindicationThis section has been translated automatically.
Hypersensitivity to the active substance, pregnancy, delirium, predelirium, narrow-angle glaucoma, epilepsy, mental illness, severe liver and kidney disease, prostate hypertrophy.
PreparationsThis section has been translated automatically.
PK-Merz
LiteratureThis section has been translated automatically.
- Gibbs MB et al (2005) Livedo reticularis: an update. J Am Acad Dermatol 52: 1009-1019
TablesThis section has been translated automatically.
Interactions of amantadine
Alcohol |
Alcohol tolerance ↓, mutual toxicity ↑ |
Amfepramon |
Delirium |
Anticholinergics |
nightmares, hallucinations |
Appetite suppressant |
Mutual toxicity ↑ |
L-Dopa |
mutual effect ↑ |
Fenproporex |
Mutual toxicity ↑ |
Ipratropium bromide |
anticholinergic effect ↑ |
Mazindol |
Mutual toxicity ↑ |
Mefenorex |
Mutual toxicity ↑ |
Memantine HCl |
Mutual toxicity ↑ |
Mephentermin-HCl |
Mutual toxicity ↑ |
Mequitazine |
Amantadine effect ↓ |
D-norpseudoephedrine |
Mutual toxicity ↑ |
Pentorex |
Mutual toxicity ↑ |
L-Propylhexedrine |
Mutual toxicity ↑ |
Propantheline Bromide |
anticholinergic effect ↑ |
Scopolamine |
anticholinergic effect ↑ |
Selegiline HCl |
Amantadine toxicity ↑ |
Sympathomimetics |
Mutual toxicity ↑ |
Tromantadine HCl |
Cross Allergy |