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Adenocarcinoma, primarily mucinousC80
Synonym(s)
Carcinoma mucinous eccrine; Cutaneous mucinous carcinoma; Mucinous eccrine carcinoma
DefinitionThis section has been translated automatically.
Relatively rare mucinous tumor of the eccrine glands. Occasionally regional lymph node metastases, very rarely more extensive metastases. Important differential diagnosis is the metastatic mucinous adenocarcinoma, mostly from the intestine.
LocalizationThis section has been translated automatically.
Eyelids, neck, capillitium, rarely trunk, feet, vulva.
Clinical featuresThis section has been translated automatically.
Deeply cutaneous, only slowly growing, 0.2-1.0 cm large, firm, painless lump. The clinical symptoms are not very specific, so that the histological findings are random.
HistologyThis section has been translated automatically.
- Irregularly arranged tumor clusters in the middle and deep dermis, in which nests or strands of epithelia are embedded in a broad mucinous stroma. The mucinous areas are often subdivided by fine bony tissue septums. More rarely, the epithelial tumor clusters come into direct contact with the surrounding connective tissue.
- Detection of myoepithelial cells using the immune markers calponin, CK5/6 or p63.
LiteratureThis section has been translated automatically.
- Qureshi H et al (2004) Primary cutaneous mucinous carcinoma: Presence of myoepithelial cells as a clue to the cutaneous origin. At J Dermatopathol 26: 353-358