Acetylation

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

Dieser Artikel auf Deutsch

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

The attachment of an acetyl group to a molecule is called acetylation in organic chemistry. The acetylation of a protein is catalysed by enzymes (acetylases). The cleavage of the acetyl group, the deacetylation, is catalysed by deacetylases (also deacetylases). Acetylation by N-acetyltransferases 1 and 2 plays an important role in the metabolism (detoxification) of drugs or contact allergens (e.g. phenylenediamine) (see below N-acetyltransferases and their coding genes NAT1 and NAT2).

Authors

Last updated on: 29.10.2020