Nonoxinol 9
Synonym(s)
DefinitionThis section has been translated automatically.
Nonoxinol 9 is a non-ionic surfactant from the group of nonylphenol ethoxylates. It is used as an active ingredient in locally applied contraceptives because of its spermicidal effect. Nonoxinol is a clear, colourless to light yellow, viscous liquid.
Field of application/useThis section has been translated automatically.
Spermicidal action: Nonoxinol-9 attacks the membrane of the sperm. If the membrane is destroyed, the sperm are immobilized. Nonoxinol-9 is contained in many creams, gels, contraceptive suppositories and foams.
Antiviral effect: Laboratory tests have shown that nonoxinol-9 also attacks the membrane of the HIV virus; on the other hand, a vaginal wall attacked by nonoxinol-9 is also much more permeable to all types of viruses, so that there is practically no protection against viruses.
Undesirable effectsThis section has been translated automatically.
Frequent use leads to local irritation of the vaginal mucosa. Nonoxinol-9 may increase the infectiousness for sexually transmitted diseases if used frequently. There is also statistical evidence of a link between nonoxinol-9 use and urinary tract infections. Allergic reactions also occur in rare cases.