Diethylamino hydroxybenzoyl hexyl benzoate*

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

Dieser Artikel auf Deutsch

Synonym(s)

2-[4-(diethylamino)-2-hydroxybenzoyl]benzoic acid hexyl ester; DHHB; Diethylaminohydroxybenzoylhexylbenzoate; Uvinul A Plus

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

Diethylamino hydroxybenzoyl hexyl benzoate, DHHB for short, is a substituted benzophenone used as a UV filter in sunscreens. While the benzophenone structural unit is responsible for UV absorption, the hydrophobic substituents ensure oil solubility and water resistance in dermatological and cosmetic preparations. DHHB has a relatively broad UV absorption spectrum (in the range 340-400 nm) with an absorption maximum λmax in the UV-A range at 354 nm. It can be combined with other UV absorbers (Kawakami CM et al. 2017). In dermal preparations DHHB does not penetrate intact skin but remains in the outer layer (stratum corneum - T. Haque JM et al. 2016). The allergenic potential is negligible. The biodegradability of diethylamino hydroxybenzoyl hexyl benzoate is considered critical in surface waters.

LiteratureThis section has been translated automatically.

  1. Haque JM et al (2016) Chemical ultraviolet absorbers topically applied in a skin barrier mimetic formulation remain in the outer stratum corneum of porcine skin. Int J Pharm 510: 250-254.
  2. Kawakami CM et al. (2017) Diethylamino hydroxybenzoyl hexyl benzoate (DHHB) as additive to the UV filter avobenzone in cosmetic sunscreen formulations - Evaluation of the photochemical behavior and photostabilizing effect. Eur J Pharm Sci 99:299-309.

Authors

Last updated on: 29.10.2020