Amides are chemical compounds that are formally derived from ammonia (NH3). In the amide structure, a hydrogen atom of ammonia is replaced by an acid residue.
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Amide
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Examples of amide compounds:
- Carboxylic acid amide: the hydrogen atom of ammonia is replaced by a carboxylic acid residue (see figure)
- Peptides and proteins contain peptide bonds. Peptide bonds are also amide bonds. Peptides and proteins are also carboxylic acid amides.
- Sulphonic acid amides are found as derivatives of sulphonic acids in some drugs, such as the sulphonamides (see figure)
- Phosphoric acid amides are found as derivatives of phosphoric acids in some drugs, e.g. in cyclophosphamide and ifosfamide.