Rhinitis drug-inducedL27.0

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Privinism

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DefinitionThis section has been translated automatically.

Non-IgE-mediated, inflammatory or nerve-reflective reaction of the nasal mucosa (see also ADR), which can be attributed to the intake of certain normally dosed drugs (see also rhinitis, pseudoallergic).

ClassificationThis section has been translated automatically.

Rhinopathic side effects caused by drugs (varies according to C.Bachert et al. 2000)
Substance/Group Active principle AAW
Central alpha sympathomimetics
Clonidine Decrease of the sympathetic tone Obstruction/pain
Antisympathomimetics
Reserpin Decrease of the sympathetic tone Obstruction/pain
Antisympathomimetics
Reserpin Emptying the norepinephrine reservoir Obstruction
Guanethidine Inhibition of release, emptying of the norepinephrine storage Obstruction
Methyldopa Formation of alpha-methyl-noradrenalin Obstruction
Anticholinergics
Atropine Anticholinergic effect Stuffy dry nose
Scopolamine Anticholinergic effect Stuffy dry nose
Antihistamines
Diphenhydramine Anticholinergic effect Stuffy dry nose
Ketotifen Anticholinergic effect Stuffy dry nose
Antidepressants
Amitryptilin Anticholinergic effect Stuffy dry nose
ACE inhibitors
Captopril Reduction of the bradykinin metabolism Sniffles

Note(s)This section has been translated automatically.

This form of rhinitis must be distinguished from irritant toxic rhinitis, also known as rhinitis medicamentosa, which is caused by an "overdose" of decongestant nasal drops (old name: privinism).

LiteratureThis section has been translated automatically.

  1. Settipane RA (2011) Other causes of rhinitis: mixed rhinitis, rhinitis medicamentosa, hormonal rhinitis, rhinitis of the elderly, and gustatory rhinitis. Immunol Allergy Clin North Am 31:457-467.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer