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Igm
Synonym(s)
DefinitionThis section has been translated automatically.
IgM, also called immunoglobulin M, is an antibody molecule whose function is to activate the complement system. An increased IgM antibody value therefore indicates an existing reaction of the immune defence.
General informationThis section has been translated automatically.
Standard value: The reference range is between 0.4 and 2.8 g/l for women and between 0.4 and 2.3 g/l for men.
Pathologically decreased: B and T cell defects, combined immunodeficiencies, viral infections, exudative enteropathy, nephrotic syndrome, burns, malignant monoclonal gammopathies, lymphatic leukemias, Hodgkin and non-Hodgkin lymphomas, drugs
Pathologically increased: malignant and benign monoclonal IgM gammopathy, acute hepatitis, chronic persistent hepatitis, infections, rheumatic diseases, liver cirrhosis, primary biliary cirrhosis, infections.
Note(s)This section has been translated automatically.
Monoclonal IgM gammopathy is present in 3.2-3.5% of >50 year olds (Grunenberg A et al. 2017)
LiteratureThis section has been translated automatically.
- Grunenberg A et al (2017) monoclonal IgM gammopathy and Waldenström's disease. Dtsch Ärztebl 114: 745-751