Coeruloplasmin

Author:Prof. Dr. med. Peter Altmeyer

Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

A copper oxidizing enzyme which is bound in the liver and migrates in the alpha2-globulin fraction in serum electrophoresis.

Its functions are:

Binding of copper (Cu) in plasma and Cu transport n tissue.
Influence on the redox status of plasma, antioxidant effect.
Acute phase protein in inflammation
Regulation of the ion ion status of iron

General informationThis section has been translated automatically.

Standard values: In serum the standard value is between 20 and 60 mg/dl or 0,94 and 3,75 µmol/l

Pathologically increased in: neoplasia, pregnancy, cholestasis, acute inflammation. In serum electrophoresis there is an increase in the alpha2-globulin fraction.

Note: The use of oral contraceptives leads to a dose-dependent 20-30% increase in serum Cp concentration.

Pathologically decreased: liver cirrhosis, nephrotic syndrome, Wilson's disease

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer