Benzodiazepines

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Preparations with sedative, and with appropriate dosage also hypnotic and anxiety and tension-relieving (anxiolytic), but also muscle-relaxing and anticonvulsive effects. Benzodiazepines are used as tranquillisers (anxiolytics), as premedication for anaesthesia, for sedation or as anticonvulsants in epilepsy.

Undesirable effectsThis section has been translated automatically.

The ability to drive is impaired; sedative effect. Danger of addiction with prolonged use (> 4 weeks). Cutaneous NW: among others urticaria, angioedema, erythema, flush, purpura, erythema exsudativum multiforme. For intoxication: respiratory depression.

InteractionsThis section has been translated automatically.

Disulfiram and omeprazole accelerate the action of diazepam, nicotine, theophylline the elimination. Metabolism is accelerated by phenobarbital and phenytoin. Mixing with other preparations in one syringe is not indicated due to chemical incompatibility.

PreparationsThis section has been translated automatically.

Diazepam, Valium, Temazepam

Note(s)This section has been translated automatically.

Antidote for poisoning: benzodiazepine antagonist, e.g. flumazenil (Anexate) i.v.

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Last updated on: 29.10.2020