Lupus erythematosus systemic Bilder

Lupus erythematosus systemic: characteristic lupus mask with persistent, succulent red plaques with fine crustal deposits.

Lupus erythematosus systemic: persistent, blurred, red, butterfly-like distributed spots in the right cheek area of a 27-year-old female patient with SLE known for years.

Systemic lupus erythematosus: multiple, chronic persistent, blurred, symmetrical, slightly burning, red (in cold environment red-livid impressing), smooth plques, variable course, activity spurts after tanning.

lupus erythematosus systemic. persistent, sharply defined, symmetrical, non-scaly erythema of the face after exposure to sunlight. known Raynaud's phenomenon. individual enanthema of the oral mucosa (hard palate and cheek mucosa). distinct disturbance of the general condition with arthralgias, fever up to 38° C. typical - butterfly pattern - ("butterfly mask") with free perioral triangle. bridge of nose, upper eyelid and tip of chin are affected.

Lupus erythematosus systemic. persistent, blurred, deep red, butterfly-like erythema in the face of a 29-year-old female patient with SLE, which has been known for years. Occasionally small papules and plaques are also found, some with firmly adhering scaling (lower lip area).

Lupus erythematosus systemic: fixed (persistent), relatively sharply defined, deep red, "butterfly-like" flake-free () erythema (the term plaque on the face of a 32-year-old female patient. SLE has been known for years. Typical is the erythema-free perioral zone and orbital region.

Systemic lupus erythematosus: after exposure to sunlight the findings worsen significantly with persistent, moderately sharply defined, symmetrical, non-scaling red plaques.

Typical - butterfly pattern - with a free perioral triangle. Bridge of nose, upper eyelids and tip of chin are affected.

Raynaud's phenomenon; disturbance of the general condition with arthralgia, fever up to 38°C.

Systemic lupus erythematosus: flat, localized, moderately sharply defined, symmetrical, moderately consistent, non-scaling red plaques.

Typical - butterfly pattern - with free perioral triangle. Bridge of nose, lips (chronic cheilitis) are also affected. Furthermore: Raynaud's phenomenon; disturbance of the AZ, arthralgia.

Systemic lupus erythematosus: flat, localized, moderately sharply defined, symmetrical, moderately consistent, non-scaling red plaques; conspicuous protrusion of the follicles (see arrow and inlet)

Systemic lupus erythematosus: Detailed view of the protruding follicular structure in the area of the lesional plaques.

Systemic lupus erythematosus: Pronounced findings with bilateral, symmetrical, flat plaque formation, fine erosions and crustal formations.

Systemic lupus erythematosus: pronounced findings with bilateral, symmetrical, flat plaque formation; fine erosions and crustal formations; detailed view.

Systemic lupus erythematosus: persistent, light-provocable, deep red plaques in the face of a 22-year-old female patient; detailed view with depiction of red lips (affected) and perioral region.

lupus erythematosus, systemic. persistent, light-provocable deep red, plaques in the face of a 22-year-old female patient. SLE known for several years. occasionally small scaly and crusty papules.

Systemic lupus erythematosus: Pronounced findings with bilateral, symmetrical, flat plaques; flat scarring.

Systemic lupus erythematosus: advanced systemic lupus erythematosus associated with scarring.

Lupus erythematosus systemic: chronic cheilitis in advanced systemic lupus erythematosus.

Lupus erythematosus, systemic: detailed view

Systemic lupus erythematosus. acutely occurred facially emphasized symmetrical exanthema with disturbance of the general findings, medium-high fever, rheumatoid complaints. 10 year-old girl.

Systemic lupus erythematosus: changes in the oral mucosa with extensive erosions and veil-like whitish plaques; spicy and very warm food leads to considerable painful burning.

Lupus erythematosus, systemic. 29-year-old female patient with persistent, clearly progressive, painful, extensive enoral erosions (hard palate and pharyngeal ring) and livid plaquelike erythema of the lower lip.

Systemic lupus erythematosus: whitish (lichen planus-like) plaques in the area of the dental ridge. No symptoms.

Systemic lupus erythematosus: acute maculopapular exanthema, accompanied by recurrent fever attacks, fatigue and exhaustion, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-AK+. UV-relatedness of the exanthema is not detectable.

Systemic lupus erythematosus: chronic, UV-provoked, locally constant maculo-papular exanthema; concomitant: recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-AK+.

Systemic lupus erythematosus: acute maculopapular exanthema, accompanied by recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-AK+.

Systemic lupus erythematosus: detailed picture: acute maculo-papular exanthema, accompanied by recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-AK+.

Systemic lupus erythematosus: pronounced findings with bilateral, symmetrical, flat plaque formation in the décolleté. Apparent UV-emphasis. Fine central scarring in the plaques.

Systemic lupus erythematosus:chronic, locally constant exanthema consisting of spots, papules and plaques; concomitant: recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-Ak+.

Systemic lupus erythematosus: acute maculopapular exanthema, accompanied by recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-AK+.

Systemic lupus erythematosus:chronic, UV-provocable, maculo-papular exanthema; concomitant: recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-Ak+.

Systemic lupus erythematosus: Pronounced findings with bilateral, symmetrical, two-dimensional, atrophic plaques; small, whitish scarring in places.

Systemic lupus erythematosus: acute maculopapular exanthema, accompanied by recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-AK+.

Systemic lupus erythematosus: characteristic "collagenosis hands" with variable blue-red and livid-red patches. 52-year-old patient with known (since 5 years) systemic lupus erythematosus.

Lupus erythematosus systemic: characteristic "collagenosis hands" with variable blue-red and livid-red spots. 83-year-old patient with known (since several years proven) systemic lupus erythematosus.

Systemic lupus erythematosus (late onset): characteristic "collagenosis hands" with variable blue-red and livid-red patches. 83-year-old patient with known (since several years proven) systemic lupus erythematosus.

Lupus erythematosus systemic (late onset) characteristic "collagenosis hands" with persistent, acaral accentuated livid-red plaques, hypercratic nail fold and small hemorrhages. 83-year-old patient with known (since several years proven) systemic lupus erythematosus.

Systemic lupus erythematosus (late onset): chronic, sharply and bizarrely limited erythematous plaques; accompanying recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-AK+.

Systemic lupus erythematosus (late onset): chronic, blurred reddish-livid (spots) plaques; concomitant recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-Ak+.

Systemic lupus erythematosus (late onset): chronic, blurred reddish-livid plaques with spatter-like whitish spots, small erosions and crusts; accompanying recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-Ak+.

Systemic lupus erythematosus (late onset): chronic, blurred reddish-livid plaques with spatter-like whitish spots, small erosions and crusts; accompanying recurrent fever attacks, fatigue and tiredness, arthralgia, inflammation parameters +, ANA high titer positive, rheumatoid factor +, DNA-Ak+.

lupus erythematosus, systemic. skin changes induced by sunlight irradiation. slightly atrophic surface epithelium. fibrin permeated str. corneum. loose, epitheliotropic, interstitial, lymphocytic infiltrate. focal vacuum degeneration of basal epithelia (left in picture). several cytoid corpuscles.

Systemic lupus erythematosus (overview): direct immunofluorescence (DIF) with detection of the lupus band at the dermo-epidermal junction zone as well as at the BM of the follicular epithelium; the lupus band consists of deposits of immune complexes ( no basement membrane antibodies!)

Schematic representation of RNA and DNA