Trichophytia, deep generalized B35.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

malady dermatophytique (Hadida et Schousboe)

History
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Hadida et al., 1953

Definition
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Very rare dermatophyte infections spreading from skin and subcutaneous tissue, lymph nodes and internal organs.

Etiopathogenesis
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Dermatophyte infection, especially by Trichophyton schönleinii, T. verrucosum or T. violaceum with underlying defence disorder.

Clinical features
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Initially superficial tinea on the head or trunk. After years, subcutaneous abscessed nodules and lymphadenitis develop. Bones, internal organs and central nervous system may be affected.

Histology
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Therapy
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Consistent antimycotic systemic therapy with imidazole derivatives (e.g. itraconazole 2-3 times/day 100 mg p.o.).

Progression/forecast
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Often lethal.

Literature
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  1. Hadida E, Schousboe A (1957) Generalized trichophytosis with subcutaneous and ganglionic localisation caused by Trichophyton faviforme. Bull Soc Fr Dermatol Syphiligr 39: 388-391
  2. Hadida E, Marill FG, Streit R, Schousboe A (1953) Generalized favus with dermo-hypodermic and lymph node localizations. Bull Soc Fr Dermatol Syphiligr 60: 279-281

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Last updated on: 29.10.2020