Synonym(s)
HistoryThis section has been translated automatically.
DefinitionThis section has been translated automatically.
Rare solitary hemangioma occurring at any age with a characteristic clinical aspect similar to a shooting target.
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LocalizationThis section has been translated automatically.
Clinical featuresThis section has been translated automatically.
Mostly solitary, 0.2-0.5 cm in Ø, red to brown-red papule/plaque, which in some cases (about 20%) is surrounded by a narrow pale halo and a larger brownish ring (shooting disc aspect). This halo may fade or recede with time. Spontaneous regression of the hemangioma is not uncommon. 'Target-like' hemangioma.
Shallow dark brown variants may lack cocard stratification, causing them to be misrecognized as melanocytic neoplasms.
HistologyThis section has been translated automatically.
- Superficial dermis: dilated, lacunar, thin-walled vessels lined by prominent "hobnail" endothelia, few intraluminal erythrocytes. Erythrocyte extravasations and hemosiderin deposits are frequently present (see below clinic).
- Deep dermis: slit-like vascular spaces and haemosiderin deposits located between compressed collagen bundles Smooth muscle actin-positive pericytes are missing (indication of lymphatic differentiation). No mitoses or nuclear atypia.
Differential diagnosisThis section has been translated automatically.
Clinical: Kaposi's sarcoma; Meyerson's nevus; granuloma anulare.
Histological: Angiosarcoma; retiform angioendothelioma; malignant endovascular papillary angioendothelioma; lymphangioma, progressive.
TherapyThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Al Dhaybi R et al (2012) Targetoid hemosiderotic hemangiomas (hobnail hemangiomas) are vascular lymphatic malformations: a study of 12 pediatric cases. J Am Acad Dermatol 66:116-120.
- Christenson LJ et al. Trauma-induced simulator of targetoid hemosiderotic hemangioma. Am J Dermatopathol 23: 221-223.
- Cotell S et al (2003) What is your diagnosis? Targetoid hemosiderotic hemangioma. Cutis 72: 51-52
- Guillou L et al (1999) Hobnail hemangioma: A pseudomalignant vascular lesion with a reappraisal of targetoid hemosiderotic hemangioma. Am J Surg Pathol 23: 97-105
- Gutte RM et al (2014) Targetoid hemosiderotic hemangioma. Indian Dermatol Online J 5: 559-560.
Kakizaki P et al (2014) Targetoid hemosiderotic hemangioma - Case report. An Bras Dermatol 89:956-959.
- Rapini RP, Golitz LE (1990) Targetoid hemosiderotic hemangioma. J Cutan Pathol 17: 233-235.
- Santa Cruz DJ, Aronberg J (1988) Targetoid hemosiderotic hemangioma. J Am Acad Dermatol 19: 550-558.
- Zaballos P et al (2015) Dermoscopy of Targetoid Hemosiderotic Hemangioma: A Morphological Study of 35 Cases. Dermatology 231:339-344.
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Outgoing links (7)
Acquired progressive lymphangioma; Angiosarcoma of the head and face skin; Angiosarcoma (overview); Excision; Granuloma anulare classic type; Kaposi's sarcoma (overview); Meyerson-naevus;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Authors
Last updated on: 06.08.2021
Author: 
Prof. Dr. med. Peter Altmeyer
Co-Autor: 
Dr. Michael Hambardzumyan
