HistoryThis section has been translated automatically.
DefinitionThis section has been translated automatically.
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Occurrence/EpidemiologyThis section has been translated automatically.
EtiopathogenesisThis section has been translated automatically.
These are sebaceous gland complexes without hair follicles. They can be idiopathically dislocated but also occur in the context of exfoliative inflammation (e.g. in Stevens-Johnson syndrome). Occasionally eruptive ectopic sebaceous glands are observed in colon cancer (Lynch syndrome) (De Felice C et al. 2005). They have also been described in connection with Muir-Torre syndrome (Ponti G et al. 2015).
LocalizationThis section has been translated automatically.
V.a. localized at the edge of the labial red, anal funnel, glans penis ( Tyson glands), large labia and eyelids.
Not infrequently, ectopic sebaceous glands are also found in the esophagus.
The Montgomery g lands, which are arranged circularly in the areolae mammae, are erroneously included among the ectopic sebaceous glands because of their clinical aspect, since histologically they have glands comparable to an accessory nipple.
Clinical featuresThis section has been translated automatically.
Harmless, mostly multiple, up to 0.1 cm large, isolated but also aggregated to smaller beds, completely symptom-free, yellow to yellow-white, mostly hardly, occasionally also granularly palpable, reactionless nodules. On the lips the sebaceous glands are very often found in the skin-near area of the lip red, on the commissures and on the inside. Puberty seems to stimulate their appearance. Patients should be convinced of the harmlessness of the findings (see rare exceptions).
HistologyThis section has been translated automatically.
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LiteratureThis section has been translated automatically.
- De Felice C et al (2005) Fordyce granules and hereditary non-polyposis colorectal cancer syndrome. Good 54:1279-1282
- Fordyce JA (1896) A peculiar affection of the mucous membrane of the lips and the oral cavity. Journal of Cutaneous and Genitourinary Diseases (Chicago) 14: 413-419Pit-Pagola Pet al. (2011) Ectopic sebaceous glands in the esophagus. Report of three cases. Gastroenterol Hepatol 34:75-78
- Massmanian A et al (1995) Fordyce spots on the glands penis. Br J Dermatol 133: 498-500
- Moosbrugger EA et al (2011) Disseminated eruption of ectopic sebaceous glands following Stevens-Johnson syndrome. J Am Acad Dermatol 65:446-448
- Ocampo-Candiani J et al (2003) Treatment of Fordyce spots with CO2 laser. Dermatol Surgery 29: 869-871
Ponti G et al (2015) Fordyce granules and hyperplastic mucosal sebaceous glands as distinctivestigmata
in Muir-Torre syndrome patients: characterization with reflectanceconfocal
microscopy. J Oral Pathol Med 44:552-557.
Incoming links (6)Ectopic sebaceous glands; Fordyce state; Montgomery glands; Sebaceous glands; Sebaceous glands, free; Sebaceous glands, heterotopic;
Outgoing links (11)Co2 laser; Erbium yag laser; Hirsuties papillaris penis; Hirsuties papillaris vulvae; Laser; Leukoplakia; Montgomery glands; Muir torre syndrome; Syringome disseminated; Tyson glands; ... Show all
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