DefinitionThis section has been translated automatically.
Most common, stable, localized form of the plaque-type psoriasis that occurs at the predilection sites of psoriasis. Psoriasis occurring inversely, e.g. on the palms of the hands and soles of the feet, is not referred to as "psoriasis vulgaris" but as psoriasis palmaris et plantaris or also plamoplantar psoriasis.
EtiopathogenesisThis section has been translated automatically.
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ManifestationThis section has been translated automatically.
LocalizationThis section has been translated automatically.
Infestation pattern (MAPP study - 3,426 patients): elbows (46%), capillitium (45%), knees (31%), trunk (24%), face (15%), palms (12%), soles (11%), nails (11%), genital area (7%).
Joint symptoms in psoriasis patients with primary skin involvement: knee (45%), fingers (19%), hip (16%), spine (14%), ankle (11%), wrist (8%)
Clinical featuresThis section has been translated automatically.
Few to numerous, localized or disseminated, usually symmetrically distributed, whitish scaling with little or no pretreatment, differently elevated (infiltrated), sharply defined plaques of varying size (0.5cm to 10.0cm and >) and configuration (roundish or oval, map-like). Extirpation phenomenon can be triggered in herds.
With local pretreatment the clinical picture changes significantly. Flocks appear as scaleless or slightly scaly, red, sharply defined, differently raised plaques or as red spots (patches) with a smooth surface.
There is usually a low endogenous eruption pressure.
Thrust-wise progression with different thrust frequencies is characteristic.
In most cases, the Koebner phenomenon cannot be triggered in the chronic starionic form of plaque psoriasis
Complication(s)This section has been translated automatically.
- Coronary heart disease: Recent evidence suggests that psoriasis is an independent risk factor for coronary heart disease. Only 40% of psoriatics are free of coronary calcifications compared to 72% of the control group with non-psoriatics. Moreover, among psoriatics, the proportion of severe calcifications and stenoses as well as of myocardial infarctions is much higher than among non-psoriatics. An analogous risk spectrum, which is reduced during therapy with TNF-alpha blockers, is also found in patients with rheumatoid arthritis.
- Obesity: An increased BMI as well as an increased abdominal and hip circumference is significantly increased in psoriatics.
- Psoriatic patients are more likely to meet criteria for metabolic syndrome (MetS) than the average population; further, increased insulin resistance.
- Psoriatics are at increased risk for hypertension. The use of beta blockers appears to further increase the risk.
- Patients with psoriasis are more likely to develop enteritis regionalis (Crohn's disease).
- Alcohol and smoking are trigger factors for psoriasis.
TherapyThis section has been translated automatically.
Progression/forecastThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Evensen K et al Increased subclinical atherosclerosis in patients with chronic plaque psoriasis. Atherosclerosis 237:499-503
- Gisondi P (2014) Hyperuricemia in patients with chronic plaque psoriasis. Drug Dev Res 75 Suppl 1:70-72
- Mrowietz U et al (2014) Pruritus and quality of life in moderate to severe plaque psoriasis: post hoc explorative analysis from the PRISTINE study. J Eur Acad Dermatol Venereol doi: 10.1111/jdv.12761
Outgoing links (4)Crohn disease, skin alterations; Metabolic syndrome; Psoriasis (Übersicht); Psoriasis vulgaris;
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